Differences from the games, real anime, and the the re-anime

This is a list of differences between the main games and the main anime series that the anime is based on the games, but they included a lot of differences for the main anime series such as Team Rocket appeared more than the Kanto and Johto saga, Red was replaced by Ash, Orange Islands are added in the anime, Green was replaced by Ashley, Ashley's anime exclusive rivals, etc.

List of differences from the main series games
This is a list of changes happend in the anime that were got some differences from the main games.
 * Ash, Gary Oak, and Delia Ketchum replaces Red's, Blue's, and Red's mother role in the anime series.
 * Ash gets a Charmander, while Ashley gets a Pikachu.
 * Jack and John are in the series as Ash and Ashley's rivals.
 * Ash's Charizard can mega evolves.
 * Ashley's Journey is based on all the events of Ash's Journey.
 * Mosh replaces Jimmy's and Ethan's role in the anime.
 * Ash goes on a training journey to train all his pokemon alone.
 * Gary's goal is to still become a Pokemon Master while at the same time is to become a researcher like his grandfather.
 * Gary gets a Eevee instead of Squirtle.
 * Gary catches Squirtle in the wild.
 * Brendan and Lucas replaces May's and Dawn's role in the anime.
 * Iris' Axew evolves all the way to Haxorus.
 * Iris collects 8 badges and compete in Unova League.